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Saturday, September 12, 2015

A storm yesterday caused a crane to fall into Mecca’s Grand Mosque, killing 107 or more and wounding 238, according to Saudi Arabia’s Civil Defense Authority.

Civil Defense Authority director General Suleiman al-Amr, in remarks to al-Ikhbariya television, said “All those who were wounded and the dead have been taken to hospital. There are no casualties left at the location”.

The accident, which occurred yesterday afternoon, was caused by strong winds and heavy rain that led the crane to fall. Photos released of the scene showed numerous bloodied bodies and various scattered debris.

The accident occurred at a time when the mosque was relatively uncrowded. “Had it happened an hour later it would have been much worse,” Khaled Al-Maeena, editor at large at the Saudi Gazette, said. “Had it happened five hours earlier or four hours earlier, I think the death toll would have been more than a thousand.”

The crane accident comes just ten days before the beginning of the Hajj, the annual pilgrimage to Mecca, Islam’s holiest site. As undergoing a pilgrimage to Mecca is a mandatory religious duty for all Muslims who physically and financially can, millions of pilgrims arrive in Mecca each year for the Hajj. Construction was underway at the mosque in order to enlarge the mosque and improve crowd control, which has been a recurring problem during Mecca’s pilgrimages.

Wednesday, December 7, 2016

Chemotherapy is usually associated with a collection of side effects ranging from digestive problems to hair loss, but a study published this week in Human Reproduction demonstrated that female cancer patients may find they have something in common with much younger women in one specific area — their ovaries.

Scientists from the University of Edinburgh examined donated ovarian tissue from fourteen female cancer patients, most of whom had Hodgkin lymphoma, and compared it to tissue from healthy women. They found the samples from women who had been treated with a specific chemotherapeutic regimen known as ABVD not only contained greater numbers of dormant ova — egg cells — than those from women treated with harsher regimens but also more than samples from healthy women. ABVD is named for combining several drugs known as adriamycin, bleomycin, vinblastine, and dacarbazine.

These reproductive cells were not merely more plentiful in ABVD patients. They also appeared immature, “new” in the words of lead researcher Evelyn Telfer. This challenges the conventional belief that girls are born with all the ova they will ever have and the numbers can only go down as the cells are either used up by the reproductive cycle or succumb to damage or natural aging. However, further research is needed to confirm this. The study covered relatively few patients by scientific standards, and David Albertini of the Center for Human Reproduction in New York has suggested the cells may not actually be freshly grown. Instead, they may have always been there and were merely rendered more detectable by ABVD treatment.

The ability to grow new egg cells may have significant implications for women in Western societies, many of whom postpone childbearing to establish careers, sometimes into their late thirties or forties. However, Telfer warns against making use of these findings too soon: “There’s so much we don’t know about the ovary. We have to be very cautious about jumping to clinical applications.”

The experiments had been discussed earlier this year at the annual conference of the European Society of Human Reproduction and Embryology.

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

Thursday, September 16, 2010

A man shot a faculty physician as well as his own mother before killing himself at Johns Hopkins Hospital in Baltimore, Maryland. The shooting occurred on the eighth floor of the Nelson Building, the hospital’s main building. Baltimore police found the suspected shooter, who had been barricaded inside his mother’s hospital room for several hours before killing himself and his mother.

At around 11:15 a.m. EDT (1515 UTC), an unnamed doctor was shot in the chest at a patient area of the Nelson Building’s thoracic center. All major hospital facilities were placed under a lockdown, and some medical personnel were evacuated from the Nelson Building. The doctor was sent to surgery at the hospital, and police spokesperson Anthony Guglielmi said that the doctor will likely survive the incident. He was not aware of any connections between the suspect and the doctor, who was in critical condition.

A nurse at the hospital told The Baltimore Sun that the shooter was dissatisfied with how his mother had been treated and even said that he was going to jump out of a window. The nurse said that, upon hearing gunshots, she ran.

Earlier, Baltimore area police said that they were “in the process of a tactical operation” to capture the gunman, who was holed up on the eighth floor. A spokesperson for the Federal Bureau of Investigation (FBI) said that it had been assisting local police in the incident. A Johns Hopkins spokesperson had previously said that authorities had taken the shooter into custody, but police said that the report was incorrect.

The suspect, who had not taken any hostages, was described as a black man in his thirties. After a standoff lasting for three hours, law enforcement officers moved into his mother’s hospital room, and found both him and his mother dead from gunshot wounds to their heads. The suspect was first identified as 50-year-old Warren Davis, and his mother as Jean Davis. Police later said that “Warren Davis” was an alias and that his real name was not known.

Baltimore Police Commissioner Frederick Bealefeld, who said that the department is “treating this case as a murder-suicide,” said that no officers reported hearing the shots that killed the two. Police had previously said that the gunman had been shot and killed by police, but police later said that that report was incorrect.

Wednesday, January 4, 2017

A joint research team from the University of Calgary, American Museum of Natural History, and Florida State University announced on Monday that the eggs of non-avian dinosaurs such as the duck-billed dinosaur took as long as six months to hatch, far longer than had previously been believed.

Bird eggs incubate for 11 to 85 days, about half the time of most other egg-laying vertebrates. Scientists had thought dinosaur eggs were more like those of modern birds than modern reptiles, but this long hatch time is far more reminiscent of monitor lizard than magpie.

The scientists reached this conclusion by comparing CT scans of the teeth of dinosaur embryos of two different species, the Protoceratops andrewsi, which had eggs weighing under 200 grams, and Hypacrosaurus stebingeri, a type of duck-billed dinosaur that had eggs twenty times that size. They observed the von Ebner lines, patterns that form in vertebrate teeth as they grow, to determine how long the overall developmental process was taking. “They’re kind of like tree rings, but they’re put down daily,” said Florida State University co-author Gregory Erickson. “And so we could literally count them to see how long each dinosaur had been developing.” They found the Protoceratops embryo was about three months old and the Hypacrosaurus about six months.

According to the research team, this may be one reason why dinosaurs did not recover after the Cretaceous-Paleogene extinction event 65 million years ago. Both the eggs and any parents guarding them would have drawn the attention of predators and been unable to flee floods or other problems. Guardians might not have been able to move far to find food. This, researchers say, would have put dinosaurs at a disadvantage over animals with quicker-hatching eggs and their mammalian competitors.

Natural History Museum Curator and study co-author Mark Norell cites advances in imaging technology as the reason why this study is being published today: “We know very little about dinosaur embryology, yet it relates to so many aspects of development, life history, and evolution, [b]ut with the help of advanced tools like CT scanners and high-resolution microscopy, we’re making discoveries that we couldn’t have imagined 20 years ago.”

The research team plans to study more fossilized dinosaur embryo skeletons to confirm their findings. Specifically, the current study did not include the skeleton of a velociraptor or any other dinosaur considered closely related to birds.

Monday, December 3, 2007

The former Mayor of Sefton in the United Kingdom has been jailed for fraudulantly obtaining state benefits.

John Walker and his wife Catie, were found guilty of conspiracy to defraud at Liverpool Crown Court and of exaggerating ill health to obtain disability living allowance.

The Judge Brian Lewis described the fraud as “a disgraceful breach of trust”.

He was jailed for 15 months for conspiring to defraud £32,871.85 in Disability Living Allowance together with a six months concurrently sentence for conspiracy to defraud £4,000.25 in Income Support.

His wife, Catie Walker, was jailed for eight months for the DLA offence and a concurrent four months for the Income Support swindle.